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目的:观察脱钙骨治疗骨缺损的临床疗效。方法:选择我院2009年1月至2010年12月收治的35例患者的临床资料,取胎儿骨骼经去髓等制成脱钙骨;根据患者骨缺损范围,将处理过的脱钙骨剪成所需大小并填充其中,缝合骨膜覆盖。术后将手术区行加压包扎,术前2小时及术后3～7天内行常规抗感染治疗,无须应用免疫抑制剂。结果:29例患者满意,未发现免疫排斥反应,骨愈合;不满意6例,术后一周内出现低热,6例患者伤口有少量黄色液体出现,经引流及抗感染治疗后,伤口愈合;行X光片检查后,患者平均(7.8±1.7)周后植骨区有新骨形成,并与正常骨组织融为一体。经2～2.5年随访,患者植骨区成骨良好,未复发瘤体病灶。结论:脱钙骨作为一种骨缺损充填材料,在治疗骨缺损方面具有良好的临床疗效。
Objective: To observe the clinical effect of decalcified bone in the treatment of bone defect. Methods: The clinical data of 35 patients admitted to our hospital from January 2009 to December 2010 were selected, and decalcified bone was obtained from the fetus bone through demyelination. According to the scope of the patient’s bone defect, the treated decalcified bone scissors Into the desired size and fill them, suture periosteum cover. Postoperative operation band compression bandage, 2 hours before surgery and 3 to 7 days after the conventional anti-infective therapy, without the use of immunosuppressive agents. Results: 29 patients were satisfied, no immune rejection and bone healing were found. Six patients were dissatisfied with fever and fever appeared in one week after operation. A small amount of yellow liquid appeared in the wounds of 6 patients and the wounds healed after drainage and anti-infection treatment. After X-ray examination, the patients had an average of (7.8 ± 1.7) weeks after the bone graft area with new bone formation, and with the normal bone tissue integration. After 2 to 2.5 years of follow-up, the bone graft area of patients with good bone formation, no recurrence of tumor lesions. Conclusion: Decalcified bone, as a kind of bone defect filler, has good clinical efficacy in the treatment of bone defects.