目的:研究东方肉穗草的化学成分。方法:对东方肉穗草的乙醇提取物高极性部位进行色谱层析,通过硅胶柱层析及Sephadex LH-20层析进行分离纯化,根据理化性质和波谱数据鉴定化合物结构。结果:共分离得到7个酚酸类化合物,分别为:3,3′-二甲氧基鞣花酸-4′-鼠李糖苷(Ⅰ)、鞣花酸(Ⅱ)、阿魏酸(Ⅲ)、异阿魏酸(Ⅳ)、咖啡酸(V)、3,4-二羟基苯甲酸(Ⅵ)、对羟基桂皮酸(Ⅶ)。结论:化合物Ⅰ、Ⅲ、Ⅵ、Ⅶ均为首次从该属植物中分离得到。 Objective: To study the chemical constituents of Oriental Saussurea. Methods: The high polar fractions of the ethanol extracts of C. orientalis were chromatographed and purified by silica gel column chromatography and Sephadex LH-20 chromatography. The structures of the compounds were identified on the basis of physicochemical properties and spectral data. Results: A total of seven phenolic compounds were isolated, which were: 3,3′-dimethoxy ellagic acid-4′-rhamnoside (I), ellagic acid (II), and ferulic acid (III). ), isoferulic acid (IV), caffeic acid (V), 3,4-dihydroxybenzoic acid (VI), p-hydroxycinnamic acid (VII). Conclusion: Compounds I, III, VI and VII were isolated from this genus for the first time.