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目的:通过对“合理用药监测系统”(PASS)的使用,提高我院门诊医师合理用药水平。方法:对我院2008年12月-2009年3月的185903张处方通过PASS系统进行监测,并通过实际调查及与相关医生讨论对统计结果进行验证判断。结果:安装后4个月出现不合理处方数13157张占总处方数的7.1%,修正后的发生率为3.0%。结论:PASS系统对大部分医嘱中的不合理用药有预警作用,从而预防和减少药物不良事件的发生,值得临床推广应用。同时也对临床药师开展工作提供依据,但PASS系统尚存在局限性,有待进一步完善。
OBJECTIVE: To improve the rational use of medicine by our outpatient physicians through the use of “Rational Drug Use Monitoring System” (PASS). Methods: 185903 prescriptions in our hospital from December 2008 to March 2009 were monitored by PASS system, and the statistical results were verified through actual investigation and discussion with relevant doctors. Results: In the 4 months after installation, 13,157 unreasonable prescriptions accounted for 7.1% of the total number of prescriptions, and the revised incidence was 3.0%. Conclusion: The PASS system has an early warning effect on irrational drug use in most medical orders, thus preventing and reducing the occurrence of adverse drug events and deserving clinical application. At the same time, clinical pharmacists also provide the basis for their work, but the PASS system still has its limitations and needs to be further improved.