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采用流式细胞仪间接免疫荧光法检测91例初治成人急性非淋巴细胞白血病（ANLL）免疫表型。42.9％患者伴有淋系抗原（Ly+ANLL）。CD7+、CD19+及CD2+者分别为22％、13．2％及7.7％。与Ly－ANLL相比，CD7+患者外周血WBC高、CD34及P-糖蛋白表达也高（P＜0.05），CD7+ANLL之完全缓解率（CR）为35％，明显低于Ly－ANLL的73.1％（P＜0．05）。CD2表达与M3／t（15；17）及M5相关，CD19表达与t（8；21）及M5相关，CD2+与CD119+（8；21）ANLL之CR率分别为71．4％及80％，与Ly－ANLL无明显差异（P＞0.05）。不伴t（8；21）异常CD19+患者的CR率28．6％，明显低于Ly-ANLL（P＜0．05）。结果表明Ly+ANLL具有独特的临床及生物学特征。
Flow cytometry indirect immunofluorescence was used to detect the immunophenotype of 91 cases of untreated adult acute nonlymphocytic leukemia (ANLL). 42.9% of patients were associated with lymphocytic antigen (Ly+ANLL). CD7+, CD19+, and CD2+ were 22%, 13.2%, and 7.7%, respectively. Compared with Ly-ANLL, CD7+ patients had high WBC count, high expression of CD34 and P-glycoprotein (P<0.05), and CD7+ANLL had a complete response rate (CR) of 35%, which was significantly lower than that of Ly-ANLL. 73.1% (P<0.05). CD2 expression was associated with M3/t(15;17) and M5, CD19 expression was associated with t(8;21) and M5, and the CR rates of CD2+ and CD119+(8;21)ANLL were 71.4% and 80%, respectively. There was no significant difference from Ly-ANLL (P>0.05). The CR rate of CD19+ patients without t(8;21) abnormalities was 28.6%, which was significantly lower than that of Ly-ANLL (P<0.05). The results show that Ly+ANLL has unique clinical and biological characteristics.