论文部分内容阅读
目的分析和总结山东省济宁市某区4 890对计划怀孕夫妇乙肝病毒的感染状况,为本地区孕前优生健康指导、控制乙肝病毒传播和实施母婴传播阻断提供参考依据。方法对2015-2016年在济宁市妇幼保健计划生育服务中心进行免费孕前优生健康检查的4 890对夫妇用酶联免疫吸附试验(EILSA法)检测乙肝五项:乙肝表面抗原(HBs Ag)、表面抗体(HBs Ab)、e抗原(HBe Ag)、e抗体(HBe Ab)、核心抗体(HBc Ab),并对于检测结果进行回顾性统计学分析。结果受检人群乙肝病毒感染率5.7%,并经临床进一步确诊,男性高于女性。乙肝表面抗体阳性(包括单纯打过疫苗的阳性和感染乙肝并产生抗体)者占51.9%。未感染乙肝病毒同时抗体阴性者占42.4%。结论本研究发现本地区近两年来孕前夫妇乙肝病毒感染率暂低于全国平均水平,但未感染者中抗体阴性者比例较高。
Objective To analyze and summarize the status of hepatitis B virus infection in couples under planned pregnancy in 4 890 in Jining City, Shandong Province, and provide references for the health guidance, prenatal eugenics control, hepatitis B virus transmission and the implementation of maternal and infant transmission in this region. Methods A total of 4 890 couples who underwent free pre-pregnancy eugenics checkup in Jining Maternal and Child Health Family Planning Service Center during 2015-2016 were tested for five hepatitis B virus (HBsAg) by enzyme-linked immunosorbent assay (ELISA) Antibodies (HBs Ab), e antigen (HBe Ag), e antibody (HBe Ab) and core antibody (HBc Ab) were measured and the results were retrospectively analyzed. Results Hepatitis B virus infection rate of 5.7% of the subjects tested, and further confirmed by clinical, men than women. Hepatitis B surface antibody positive (including a single vaccine-positive and infected with hepatitis B and produce antibodies) accounted for 51.9%. Infected with hepatitis B virus at the same time negative antibody accounted for 42.4%. Conclusions This study found that in the past two years in our region, the prevalence of HBV infection in couples during the last two years was temporarily below the national average, but the proportion of those with negative antibodies in those who were not infected was higher.