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目的:观察氟脲嘧啶(5—Fu)+顺铂(DDP)腹腔内注射治疗进展期胃癌。方法:选择有明确的病理诊断分型及客观的肿瘤测量指标,对28例进展期胃癌患者腹腔内注射5-Fu+DDP,并头低脚高位。结果:显效4例,有效9例,总有效率46.4%,较长生存者26个月,中位生存11个月,对原发癌、淋巴转移及腹膜转移较好,对肝、肝门及胰转移亦有一定效果。结论:5-Fu+DDP对进展期胃癌疗效较好,易操作,副作用小,费用低,对基层医院治疗进展期胃癌有实用价值。
Objective: To observe the intraperitoneal injection of fluorouracil (5-Fu) + cisplatin (DDP) for the treatment of advanced gastric cancer. Methods: Select a clear pathological diagnosis and objective tumor measurement indicators, 28 patients with advanced gastric cancer intraperitoneal injection of 5-Fu + DDP, head and low head high. Results: 4 cases were markedly effective, 9 cases were effective, the total effective rate was 46.4%, the long survival was 26 months, the median survival was 11 months, and the primary cancer, lymphatic metastasis, and peritoneal metastasis were better. Portal and pancreatic metastasis also have a certain effect. Conclusion: 5-Fu+DDP has good curative effect on advanced gastric cancer, easy operation, small side effects and low cost. It has practical value for the treatment of advanced gastric cancer in primary hospital.