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目的：探讨肥大细胞与涎腺上皮组织源性良恶性肿瘤的关系。方法：采用图像分析系统，对５５例涎腺良恶性肿瘤及正常组织中肥大细胞的分布、形态进行了观察，测定肥大细胞的数目、大小。结果：肥大细胞在恶性肿瘤中分布、形态及功能活性均不同于正常组织和良性肿瘤，主要表现在细胞分布范围广、呈密集状态、形态不一、大小不等和脱颗粒现象多见等方面；恶性肿瘤中肥大细胞在单位面积内的最大分布密度和细胞体积要大于正常组织。结论：肥大细胞在涎腺上皮组织源性恶性肿瘤中，功能活性增高。
Objective: To investigate the relationship between mast cells and salivary gland epithelial tissue-derived benign and malignant tumors. Methods: The distribution and morphology of mast cells in 55 salivary gland benign and malignant tumors and normal tissues were observed by image analysis system. The number and size of mast cells were measured. Results: The distribution, morphological and functional activities of mast cells in malignant tumors were different from those in normal tissues and benign tumors, mainly in the areas of wide distribution, dense state, different morphology, size and degranulation ; The maximum distribution density and cell volume of mast cells in unit area in malignant tumors should be larger than normal tissues. Conclusion: Mast cells in salivary gland epithelial tissue-derived malignancies, functional activity increased.