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目的分析探讨干扰素联合丙种球蛋白对儿童传染性单核细胞增多症的临床治疗效果。方法对照组(n=30)传染性单核细胞增多症患儿利巴韦林治疗,同时给予观察组(n=35)患儿干扰素联合丙种球蛋白治疗,对比治疗效果。结果①对照组总有效率70.0%(21/30),观察组总有效率91.4%(32/35);观察组总有效率显著高于对照组(P<0.05);②两组的不良反应发生率差异无显著性(P>0.05)。结论干扰素联合丙种球蛋白治疗是治疗儿童传染性单核细胞增多症的理想方案。
Objective To investigate the clinical effect of interferon combined with gamma globulin on childhood infectious mononucleosis. Methods The control group (n = 30) was treated with ribavirin in children with infectious mononucleosis. The patients in the observation group (n = 35) were treated with interferon plus gamma globulin. The therapeutic effect was compared. Results ① The total effective rate in the control group was 70.0% (21/30), and the total effective rate in the observation group was 91.4% (32/35). The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). ② The adverse reactions The incidence was not significantly different (P> 0.05). Conclusion The combination of interferon and gamma globulin is an ideal treatment for childhood infectious mononucleosis.