论文部分内容阅读
目的:探讨主动免疫联合中药复方对复发性自然流产患者内分泌-免疫系统的调节。方法:将66例不明原因习惯性流产患者随机分成两组。对照组31例妊娠后给予肌注黄体酮及HCG安胎治疗至妊娠3个月,治疗组接受主动免疫联合中药复方治疗,妊娠后给予药物治疗至妊娠3个月。结果:治疗后治疗组血孕酮及血βHCG与对照组差异无统计学意义,治疗后治疗组CD3+、CD4+细胞较对照组下降(P<0.05),CD8+细胞、CD4+/CD8+较对照组升高,两组差异有统计学意义。结论:主动免疫联合中药复方对复发性自然流产患者的内分泌免疫有调节作用,提高临床妊娠成功率。
Objective: To investigate the regulation of endocrine-immune system in patients with recurrent spontaneous abortion by active immunization combined with traditional Chinese medicine. Methods: 66 cases of unexplained habitual abortion were randomly divided into two groups. Control group, 31 cases of pregnancy after intramuscular injection of progesterone and HCG tocolysis to pregnancy 3 months, the treatment group received active immunization combined with traditional Chinese medicine compound therapy, pregnancy medication given until 3 months of pregnancy. Results: After treatment, there was no significant difference between the serum progesterone and serum βHCG in the treatment group and the control group. After treatment, the levels of CD3 + and CD4 + cells in the treatment group decreased (P <0.05), and the levels of CD8 + cells and CD4 + / CD8 + , The difference between the two groups was statistically significant. Conclusion: The combination of active immunization and traditional Chinese medicine regulates endocrine immunity in patients with recurrent spontaneous abortion and improves the success rate of clinical pregnancy.