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目的:观察中西医结合疗法(六味安消胶囊、铝碳酸镁、吗丁啉)治疗胆汁反流性胃炎的临床疗效。方法:将192例符合入选标准的胆汁反流性胃炎患者随机分为观察组和对照组各96例。对照组口服铝碳酸镁、吗丁啉;观察组口服铝碳酸镁、吗丁啉、六味安消胶囊。两组均7 d为1个疗程,治疗2个疗程后观察患者隐痛、饱胀、嗳气、反酸苦水等临床症状的改善及临床疗效。结果:观察组治愈率72.92%,总有效率95.83%;对照组治愈率50.00%,总有效率75.00%。治愈率、总有效率两组相比有明显差异(P<0.05)。两组隐痛、饱胀、嗳气、反酸苦水等指标治疗前后比较差异显著(P<0.05),且观察组改善优于对照组(P<0.05)。两组均未发现明显的不适症状及不良反应。结论:中西医结合疗法(六味安消胶囊、铝碳酸镁、吗丁啉)治疗胆汁反流性胃炎临床疗效显著,不良反应小,可较好地改善临床症状。
Objective: To observe the clinical curative effect of combined traditional Chinese and western medicine (Liuwei Anxiao Capsule, aluminum magnesium carbonate and domperidone) in the treatment of bile reflux gastritis. Methods: A total of 192 patients with bile reflux gastritis who met the inclusion criteria were randomly divided into observation group (96 cases) and control group (96 cases). Control group oral magnesium carbonate, domperidone; observation group oral magnesium carbonate, domperidone, Liu Wei Anxiao capsules. Both groups were treated for 7 days for one course of treatment. After two courses of treatment, the clinical symptoms such as pain, fullness, belching and acid reflux were observed and the clinical effects were observed. Results: The cure rate in observation group was 72.92%, the total effective rate was 95.83%. The cure rate in control group was 50.00% and the total effective rate was 75.00%. Cure rate, total effective rate was significantly different between the two groups (P <0.05). The two groups of pain, fullness, belching, acid and bitter water and other indicators before and after treatment were significantly different (P <0.05), and the observation group improved better than the control group (P <0.05). No obvious symptoms and adverse reactions were found in both groups. Conclusion: The combination of traditional Chinese and western medicine (Liuwei Anxiao Capsule, aluminum magnesium carbonate, domperidone) in the treatment of bile reflux gastritis has significant clinical curative effect and small adverse reactions, which can improve the clinical symptoms.