甲状腺机能亢进(简称甲亢)合并特发性血小板减少性紫癜(ITP)临床陆续见有报道,而桥本氏病甲状腺功能减退(简称甲减)合并ITP尚未见报道,我们收治1例,现报告如下。患者女性,54岁。因甲状腺肿大30年于1987年10月22日入院。入院后给予甲状腺片20mg/日治疗,效果欠佳,1987年11月7日出现全身散在性出血点及瘀斑。体检:呈甲减外貌,全身皮肤粘膜散在性瘀点,四肢可见片状瘀斑。甲状腺Ⅲ°肿大,质硬,结节状,无震颤及血管杂音。实验室检查:红细胞4.0×10~(12)/L,血红蛋白120g/L,白细胞6.0×10~9/L,血小板20×10~9/L。抗血小板糖蛋白Ⅲa自身抗体180.2％(> Hyperthyroidism (referred to as hyperthyroidism) with idiopathic thrombocytopenic purpura (ITP) have been reported in succession, and Hashimoto’s thyroidism hypothyroidism (referred to as hypothyroidism) with ITP has not been reported, we admitted to a case, the report is now as follows. Patient female, 54 years old. Thirty years after thyroid enlargement was admitted on October 22, 1987. After admission to give thyroid tablets 20mg / day treatment, the effect is poor, November 7, 1987 systemic scattered bleeding and ecchymosis. Physical examination: hypothyroidism appearance, systemic skin and mucous membrane scattered petechia, flaky ecchymosis visible limbs. Thyroid enlargement Ⅲ °, hard, nodular, no tremor and vascular murmur. Laboratory tests: red blood cells 4.0 × 10-12 / L hemoglobin 120g / L, white blood cells 6.0 × 10 ~ 9 / L, platelets 20 × 10 ~ 9 / L. Anti-platelet glycoprotein Ⅲ a autoantibodies 180.2% (>