论文部分内容阅读
目的探讨血清糖化白蛋白(GA)在老年2型糖尿病并肠内营养患者血糖管理中的价值。方法收集老年2型糖尿病并肠内营养患者30例,分别在入院第2天、2周、1个月、2个月、3个月空腹8 h以上采取静脉血,测定GA、空腹血糖(FBG)、糖化血红蛋白(Hb A1c)、糖化血清蛋白(GSP)、血清总白蛋白(ALB)及血红蛋白(HGB)等相关指标;各时间段ALB≥35 g/L为正常白蛋白组(A组),血清白蛋白<35 g/L为低白蛋白组(B组),对数据进行统计分析。结果 B组2周、1个月、2个月、3个月GA明显高于A组,B组入院第2天、1个月、2个月、3个月HGB明显低于A组,差异均有统计学意义(均<0.05);两组1个月、2个月、3个月FBG差异均有统计学意义(均<0.05);两组入院第2天、2周、1个月Hb A1c差异均有统计学意义(均<0.05)。见表1。GA与各组ALB、FBG、Hb A1c均有显著相关性(均<0.05)。结论 GA可作为评价糖尿病合并营养不良患者短时期平均血糖水平的可靠指标。
Objective To investigate the value of serum glycosylated albumin (GA) in the management of blood glucose in elderly patients with type 2 diabetes mellitus and enteral nutrition. Methods 30 elderly patients with type 2 diabetes mellitus and enteral nutrition were enrolled in this study. Venous blood was taken at 8 days after admission on day 2, 2, 1, 2 and 3 months after admission. The levels of GA, fasting blood glucose (FBG) Hb A1c, GSP, ALB and HGB were detected in all the subjects. ALB (35 g / L) was normal albumin (A) , Serum albumin <35 g / L for the low albumin group (B group), the data for statistical analysis. Results The levels of GA in group B at 2 weeks, 1 month, 2 months and 3 months were significantly higher than those in group A, while those in group B at 2 days, 1 month, 2 months and 3 months after admission were significantly lower than those in group A (All P <0.05). The FBG differences at 1, 2 and 3 months in both groups were statistically significant (all <0.05). The two groups were admitted to the hospital on day 2, 2 and 1 Hb A1c differences were statistically significant (all <0.05). See Table 1. GA was significantly correlated with ALB, FBG and Hb A1c in all groups (all <0.05). Conclusion GA can be used as a reliable indicator to evaluate the short-term average blood glucose level in diabetic patients with malnutrition.