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目的观察口服四妙勇安汤与局部臭氧注射治疗类风湿炎关节疼痛的疗效。方法将76例类风湿关节炎患者按就诊顺序随机分为治疗组与对照组,每组38例。治疗组采用加减四妙勇安汤配合局部臭氧注射,对照组采用西医常规治疗,口服甲氨蝶片、来氟米特片及双氯芬酸钠缓释片治疗。连续治疗1个月后评定疗效。结果治疗组总有效率为94.7%,对照组为86.8%,经统计学处理,有显著性差异(P<0.05);与治疗前比较,两组患者在“休息痛指数”、“关节压痛指数”及“关节肿胀指数”改善上有显著性差异(P<0.05),与治疗后比较,治疗组在“休息痛指数”和“关节压痛指数”改善上优于对照组(P<0.05)。结论与常规西药治疗组比较,四妙勇安汤与局部臭氧注射治疗疗效更优,能更有效地改善患者的临床症状。
Objective To observe the effect of oral administration of Simiao Yongan Decoction and local ozone injection on rheumatoid arthritis pain. Methods 76 cases of rheumatoid arthritis patients were randomly divided into treatment group and control group, with 38 cases in each group. The treatment group with addition and subtraction Simiao Yongan soup with local ozone injection, the control group with conventional Western medicine, oral methotrexate, leflunomide tablets and diclofenac sodium sustained-release tablets. After 1 month of continuous treatment to assess the efficacy. Results The total effective rate was 94.7% in the treatment group and 86.8% in the control group, which was significantly different (P <0.05) by statistical analysis. Compared with those before treatment, (P <0.05). Compared with the control group, the treatment group showed significant improvement on the improvement of “resting pain index” and “joint tenderness index” Better than the control group (P <0.05). Conclusion Compared with the conventional western medicine group, Simiao Yongan Decoction and topical ozone injection have better curative effect and can effectively improve the clinical symptoms of patients.