Prostaglandins(PGs) constitute a family of unsaturated fatty acids witha 20-carbon skeleton. Prostaglandins are found in almost every mammaliancell and are considered locally acting hormones (autocoids). They aresynthesized on demand and subsequently destroyed near the site of theirsynthesis. Since the early 1960’s, increasing evidence has implicated theimportance of PGs in several physiological processes affecting the gastroin- Prostaglandins are found in almost every mammaliancell and are considered locally acting hormones (autocoids). They aresynthesized on demand and subsequently destroyed near the site of theirsynthesis. Since the early 1960’s, increasing evidence has implicated theimportance of PGs in several physiological processes affecting the gastroin-