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目的:分析临床药师对I类切口围手术期患者预防用抗菌药物的干预效果,为合理使用抗菌药物提供参考。方法:选取2015年7—12月间医院外科I类切口手术患者296例作为对照组;另选2016年3—8月间I类切口手术患者210例作为干预组,比较两组患者预防用抗菌药物的使用率、合理率及抗菌药物使用平均费用。结果:干预组患者抗菌药物使用率为24.29%低于对照组为88.18%(P<0.05),使用合理率为83.40%高于对照组为56.18%(P<0.05);抗菌药物使用平均费用为(768.00±42.00)元低于对照组为(1 526.00±78.00)元(P<0.05)。结论:通过临床药师干预,能够有效降低外科I类切口围手术期患者抗菌药物的使用率,提高外科I类切口围手术期抗菌药物使用的合理性,降低患者的药品费用,促进了临床抗菌药物的合理使用。
OBJECTIVE: To analyze the intervention effect of clinical pharmacists on preventive antibacterials in perioperative patients with type I incision, and provide references for the rational use of antibacterials. Methods: Totally 296 patients with type I incision in hospital surgery from July to December in 2015 were selected as the control group. Another 210 patients with type I incision in March-August 2016 were selected as the intervention group. Drug usage, reasonable rates, and average cost of antimicrobial use. Results: The use of antibacterials in intervention group was lower than that in control group (24.29%, 88.18%, P <0.05), and the rational use rate was 83.40% (56.18%, P <0.05). The average cost of antibacterial was (768.00 ± 42.00) yuan lower than the control group (1 526.00 ± 78.00) yuan (P <0.05). Conclusion: The clinical pharmacist intervention can effectively reduce the usage of antimicrobial agents in perioperative patients with surgical incision I, improve the rationality of perioperative antimicrobial use in class I incision, reduce the cost of drugs for patients and promote the development of clinical antibacterial drugs The rational use of.