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[目的]调查成都市10所医院清洁切口围手术期预防使用抗菌药物情况,为合理使用手术预防用药提供依据。[方法]对成都市10所二甲及以上医院所有清洁切口术后住院病人进行调查,术后抗菌药物未停用者1周后追踪完成调查,分析其中清洁切口围手术期预防使用抗菌药物情况。[结果]共调查453例清洁切口术后患者,403例预防使用了抗菌药物;抗菌药物术前使用率59.55%(单联用药79.14%)、术中使用率11.41%(单联用药80.43%)、术后使用率99.50%(双联用药41.40%、三联及以上用药11.72%);只有26.13%的手术持续时间﹥3h患者术中接受了抗菌药物;42.50%的术前用药时间超过24h,92.51%的术后用药时间超过48h。[结论]本次调查揭示了本地区清洁切口围手术期预防抗菌药物使用率高,用药指征不严,用药时机不当,用药疗程长,联合用药不合理,应采取措施加强抗菌药物的合理应用。
[Objective] To investigate the perioperative prophylactic use of antibacterials in clean incisions in 10 hospitals in Chengdu, and provide the basis for the rational use of surgical prophylaxis. [Method] The investigation of all postoperative inpatients with clean incision in 10 hospitals of Grade A and above in Chengdu City was conducted. After 1 week of follow-up, the antibacterials were followed up to investigate the prevention of antibacterial drugs during perioperative period . [Results] A total of 453 patients undergoing clean incision were enrolled and 403 patients were prevented from using antibacterial drugs. The preoperative use rate of antimicrobial agents was 59.55% (single drug use was 79.14%), the intraoperative usage rate was 11.41% (80.43% , And the rate of postoperative use was 99.50% (41.40% for double-drug treatment and 11.72% for triple-drug treatment or above); only 26.13% of patients underwent operation for 3 hours. Patients received antimicrobial drugs intraoperatively, 42.50% % Of the postoperative medication more than 48h. [Conclusion] This investigation revealed that perioperative clean incision in the region should be taken to improve the rational use of antimicrobial agents by preventing the use of antibacterials in perioperative period with high utilization rate, lax indications, improper timing of medication, long course of treatment and unreasonable combination therapy .