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目的探讨疏肝健脾益肾中药联合化疗治疗肝郁型转移性三阴性乳腺癌的临床效果。方法 50例肝郁型转移性三阴性乳腺癌患者,随机分成对照组和观察组,每组25例。对照组采用化疗治疗,观察组采用疏肝健脾益肾中药联合化疗治疗。比较两组患者的临床疗效以及毒副作用。结果观察组缓解率为64.00%,高于对照组的32.00%(P<0.05);观察组骨髓抑制程度、消化道毒副作用发生程度均低于对照组(P<0.05)。结论运用疏肝健脾益肾中药联合化疗治疗肝郁型转移性三阴性乳腺癌患者能有效缓解患者病情,且安全性较高,值得临床推广应用。
Objective To investigate the clinical effects of Shugan Jianpi Yishen combined with chemotherapy in the treatment of liver depression metastatic triple negative breast cancer. Methods Fifty cases of liver metastasis of triple negative breast cancer patients were randomly divided into control group and observation group, 25 cases in each group. The control group was treated with chemotherapy, and the observation group was treated with Shugan Jianpiyishen combined with chemotherapy. The clinical efficacy and side effects of the two groups were compared. Results The remission rate in the observation group was 64.00%, which was higher than that in the control group (32.00%, P <0.05). The degree of myelosuppression and gastrointestinal side effects in the observation group were lower than those in the control group (P <0.05). Conclusion Shugan Jianpi Yishen combined with chemotherapy in patients with liver depression and metastatic triple negative breast cancer patients can effectively alleviate the patient’s condition, and the safety is high, worthy of clinical promotion and application.