论文部分内容阅读
目的 :评价国产头孢丙烯片剂治疗呼吸道感染的疗效与安全性。方法 :头孢丙烯片与头孢克洛胶囊随机对照治疗下呼吸道感染 10 1例 ,头孢丙烯组 5 1例 (男性 33例 ,女性 18例 ,年龄 5 0a±s 13a) ,头孢克洛组 5 0例 (男性 2 9例 ,女性 2 1例 ,年龄4 9a± 15a)剂量分别均为 5 0 0mg ,po ,bid及tid ;另用头孢丙烯片 5 0 0mg ,po ,qd开放治疗上呼吸道感染 5 5例 ;疗程均 7～ 14d。结果 :头孢丙烯和头孢克洛治疗下呼吸道感染的有效率分别为 94 %及92 % ,细菌清除率均为 93% ,不良反应发生率分别为 10 %及 8% ,2组比较差异均无显著意义 ,P >0 .0 5。头孢丙烯开放治疗上呼吸道感染 5 5例的有效率为 94 % ,细菌清除率为 90 % ,不良反应发生率为4 %。结论 :头孢丙烯片剂治疗呼吸道感染疗效确切 ,不良反应少见而轻微
Objective: To evaluate the efficacy and safety of domestic cefprozil tablets in the treatment of respiratory tract infections. Methods: Cefprozil tablets and cefaclor capsules were randomly divided into two groups: 101 cases of lower respiratory tract infection, 51 cases of cefprozil group (33 males and 18 females, age 50a ± s 13a) and cefaclor 50 cases (29 males and 21 females, age 49a ± 15a) were given 500 mg, po, bid and tid respectively. Cefoperazone tablets were also used for the treatment of upper respiratory tract infections Cases; treatment are 7 ~ 14d. Results: The effective rates of cefprozil and cefaclor in the treatment of lower respiratory tract infections were 94% and 92% respectively, the bacterial clearance rate was 93% and the incidence of adverse reactions were 10% and 8% respectively. There was no significant difference between the two groups Significance, P> 0 .0 5. Cefprozil open treatment of upper respiratory tract infection in 55 cases of 94% efficiency, bacterial clearance rate of 90%, the incidence of adverse reactions was 4%. Conclusion: Cefprozil tablets are effective in the treatment of respiratory tract infections with rare and mild side effects