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采用放射免疫法测定51例胃癌、33例胃良性疾病及8例消化系其它恶性肿瘤患者手术前后胃液内癌胚抗原含量。结果:胃癌组患者胃液内癌胚抗原水平明显高于其它两组,本法对胃癌诊断的敏感性为68.6%,特异性为80.5%。作者认为术前检测有助于提高胃癌诊断的正确性,而术后检测对曾行胃大部切除者已无临床意义。
Radioimmunoassay was used to determine carcinoembryonic antigen content in gastric fluid in 51 cases of gastric cancer, 33 cases of benign gastric disease and 8 cases of other malignant tumors of the digestive system before and after surgery. RESULTS: The level of carcinoembryonic antigen in gastric juice was significantly higher in patients with gastric cancer than in the other two groups. The sensitivity of this method to the diagnosis of gastric cancer was 68.6% and the specificity was 80.5%. The author believes that preoperative detection is helpful to improve the accuracy of gastric cancer diagnosis, and postoperative detection has no clinical significance for those who have undergone major gastrectomy.