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目的:探讨早期肠内营养对老年胃癌患者术后恢复的安全性和有效性。方法:回顾分析2016年1月至2016年12月收治台州医院的35例老年胃癌患者,行胃癌根治术后第一天即开始早期肠内营养支持,观察其临床症状变化,并在术前、术后第1天、术后第7天测定患者体质指数、血红蛋白、前白蛋白、血浆蛋白、肝肾功能、血糖、电解质、排气时间,观察患者7天内的死亡率、并发症。结果:研究期间所有患者临床消化道无严重并发症,无死亡,且胃肠道功能恢复较快;术前和术后的血糖、肝肾功能、电解质等比较差异无统计学意义(P>0.05);术后1天体质指数有所降低(P<0.05),而术后7天的转铁蛋白高于术前和术后1天(P<0.05)。结论:胃癌术后早期肠内营养支持安全、可行,但观察人数偏少,需进一步评价。
Objective: To investigate the safety and effectiveness of early enteral nutrition in the recovery of elderly patients with gastric cancer. Methods: From January 2016 to December 2016, 35 elderly patients with gastric cancer admitted to Taizhou Hospital were retrospectively analyzed. Early enteral nutrition support was started on the first day after radical operation of gastric cancer, and the clinical symptoms were observed. Before operation, Body mass index, prealbumin, plasma albumin, liver and kidney function, blood glucose, electrolytes and exhaust time were measured on the first day after operation and on the seventh day after operation. The mortality and complications of the patients within 7 days were observed. Results: All the patients had no serious clinical gastrointestinal complications during the study, no death and rapid gastrointestinal function recovery. There was no significant difference in blood glucose, liver and kidney function, electrolytes before and after operation between the two groups (P> 0.05 ). The body mass index decreased on the 1st postoperative day (P <0.05), while the transferrin was higher on the 7th postoperative day than preoperative and postoperative one day (P <0.05). Conclusion: The early postoperative enteral nutrition support for gastric cancer is safe and feasible, but the number of observers is small and needs further evaluation.