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报告1980～1990年经治外耳恶性黑素瘤16例,随访2～116月,初治扩大范围的肿物切除术14例;耳截除术2例。术后11例未复发;2例死于其他疾病;4例死于恶性黑素瘤;5例复发进一步手术,其中2例加用放疗。组织学分型;结节型7例;表面播散型6例;原位黑素瘤2例;雀斑恶变1例。病变厚度0.15～11.5mm。9例属Clark Ⅳ级以上。所有病例PCNA免疫染色均呈强阳性,与预后无明显关系。CD31免疫染色
Report from 1980 to 1990 by extrahepatic malignant melanoma in 16 cases, followed up for 2 to 116 months, the initial treatment of an enlarged range of tumor resection in 14 cases; 2 cases of otomy. 11 had no recurrence after operation, 2 died of other diseases, 4 died of malignant melanoma, and 5 had further surgery. Among them, 2 patients received radiotherapy. Histological classification; nodular in 7 cases; surface disseminated in 6 cases; in situ melanoma in 2 cases; freckle degeneration in 1 case. Lesions thickness 0.15 ~ 11.5mm. 9 cases are Clark Ⅳ level above. All cases of PCNA immunostaining were strongly positive, no significant relationship with the prognosis. CD31 immunostaining