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目的 探讨胆碱酯酶活性在决定有机磷农药中毒抢救中氯磷定、阿托品的用量 ,停药时间及对患者预后判断的作用。方法 将口服有机磷农药中毒抢救传统治疗组列为对照组 (32例 ) ,将口服有机磷农药中毒采用胆碱酯酶监测指导氯磷定、阿托品用量及停药列为观察组 (5 0例 )。结果 观察组阿托品用量和氯磷定用量与对照组阿托品用量和氯磷定用量有显著差异 (P <0 .0 1)。观察组治愈 5 0例 ,治愈率 10 0 % ;对照组治愈 2 8例 ,治愈率 87.5 %。结论 监测胆碱酯酶活性可决定氯磷定、阿托品用量 ,用药时间 ,杜绝阿托品过量中毒 ,显著提高抢救成功率
Objective To investigate the effects of cholinesterase activity on the determination of chlorophosphonous and atropine in the rescue of organophosphorus pesticide poisoning, the time of withdrawal and the prognosis of patients. Methods The traditional treatment of oral organophosphorus pesticide poisoning treatment group as a control group (32 cases), oral organophosphorus pesticide poisoning using cholinesterase monitoring guidance chlordecone, atropine dosage and withdrawal as observation group (50 cases ). Results The amount of atropine and the dosage of chlorophosphorus in the observation group were significantly different from those of the control group (P <0.01). In the observation group, 50 cases were cured and the cure rate was 100%. In the control group, 28 cases were cured, and the cure rate was 87.5%. Conclusion Monitoring cholinesterase activity can determine the chlorophosphonous, atropine dosage, medication time, put an end to excessive poisoning, significantly improve the success rate of rescue