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患者女,70岁,既往无药物不良反应史,及高血压等慢性疾病史。2002年6月中旬在一次健身舞表演时突发下肢不能随意活动。体检:神志清,无头晕、恶心等症状,BP 130/85mmHg,经核磁检查后确诊为腰椎滑脱。以后发展为下肢疼痛,行走困难,一侧下肢不能抬,坐立不能,平卧有时疼痛难忍。故于6月27日晚12时左右服用复方丙氧氨酚(达宁)和复方氯唑沙宗各2片,据患者自述服后3～5min后有睡意,但即刻出现幻觉。清醒后幻觉现象消失,睡时幻觉又复现,约10min后昏睡,至次日凌晨苏醒后一切正常。再次服用达宁和复方氯唑沙宗各2片,3～5mm后又出现上述情况。该患者共服用达宁4次(bid)后,于6月29日下午停服达宁,而继续服用氯唑沙宗未再出现幻觉。
Female patient, 70 years old, no past history of adverse drug reactions, and chronic diseases such as hypertension. Mid June 2002 during a fitness dance burst of lower extremities can not be free to move. Physical examination: conscious, no dizziness, nausea and other symptoms, BP 130 / 85mmHg, diagnosed by lumbar spondylolisthesis after magnetic resonance imaging. After the development of lower extremity pain, walking difficulties, one side can not lift the lower limbs, sitting can not, supine and sometimes painful. Therefore, on the evening of June 27, taking compound aprotinin (Tanin) and compound chlorzoxazone 2, according to the patient readme service after 3 ~ 5min drowsiness, but immediately hallucinations. Awake after the disappearance of hallucinations, hallucinations sleep again, about 10min after drowsiness, to wake up the next morning after all normal. Once again, taking daning and compound chlorzoxazone 2, 3 ~ 5mm after the above situation. After taking 4 doses of darun (bid), the patient stopped taking dNaning on the afternoon of June 29, and no further hallucinogenicity was observed when she continued taking chlorzoxazone.