论文部分内容阅读
目的评价并对比钬激光前列腺剜除术(Holmium laser enucleation of the prostate,HoLEP)和经尿道前列腺电切术(Transurethral resection of the prostate,TURP)治疗前列腺良性增生(Benign prostatic hyperplasia)的临床疗效。方法选择该院2010年1月—2012年12月BPH患者共128例,分别接受HoLEP(63例)或TURP(65例)治疗,评价二组患者手术前及术后3个月残余尿量(PVR)、国际前列腺症状评分(IPSS),生活质量(QOL)评分,最大尿流率(MFR)等指标,并记录术中出血量、手术时间、切除前列腺重量、膀胱冲洗时间、留置导尿时间、术后住院时间等围术期相关指标。结果术后3个月,二组PVR、IPSS、QOL、MFR等指标均较术前显著改善(P<0.05),但组间比较差异无统计学意义(P>0.05);HoLEP组术中出血量、膀胱冲洗时间、留置导尿时间、术后发生低血钠、术后住院时间、输血患者比例均显著低于TURP组(P<0.05),切除前列腺重量显著高于TURP组(P<0.05)。结论 HoLEP和TURP治疗前列腺良性增生的临床疗效相当,但HoLEP切除腺体更彻底、更安全。
Objective To evaluate and compare the clinical efficacy of holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostate (TURP) in the treatment of benign prostatic hyperplasia. Methods A total of 128 BPH patients from January 2010 to December 2012 in our hospital were enrolled in this study. The patients were treated with HoLEP (63 cases) or TURP (65 cases) respectively. The residual urine volume before and 3 months PVR, IPSS, QOL and MFR were recorded. The intraoperative blood loss, operation time, prostatectomy weight, bladder irrigation time, indwelling catheterization time , Postoperative hospitalization and other perioperative related indicators. Results The indexes of PVR, IPSS, QOL and MFR in the two groups were significantly improved (P <0.05) at 3 months after operation, but there was no significant difference between the two groups (P> 0.05). The intraoperative bleeding in the HoLEP group (P <0.05), and the weight of prostatic ablation was significantly higher than that of TURP group (P <0.05) ). Conclusion The clinical efficacy of HoLEP and TURP in the treatment of benign prostatic hyperplasia is comparable, but the removal of HoLEP is more thorough and safer.