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目的分析直肠癌术后局部复发不同治疗方法的疗效。方法回顾收治的直肠癌根治术后复发患者102例的病历资料,再次接受治疗76例,其中Ⅰ组(单纯手术)28例,Ⅱ组(手术切除加放疗)20例,Ⅲ组(单纯放疗)30例。结果Ⅰ、Ⅱ、Ⅲ及未治疗组中位存活期分别为26.8、21、14及4个月。Ⅰ组1、3年生存率显著优于Ⅲ组(P<0.05)。结论提高直肠癌复发患者的疗效关键是密切随访,早期诊断,争取手术或以手术为主的综合治疗。
Objective To analyze the curative effect of different treatment of local recurrence after rectal cancer. Methods A total of 102 patients with recurrent rectal cancer after radical resection were retrospectively reviewed. The patients were treated again in 76 cases, including 28 cases in group Ⅰ (surgery alone), 20 cases in group Ⅱ (surgery plus radiotherapy), and Ⅲ (radiotherapy alone) 30 cases. Results The median survival of Ⅰ, Ⅱ, Ⅲ and untreated groups were 26.8, 21, 14 and 4 months respectively. The 1-year and 3-year survival rates of group Ⅰ were significantly better than those of group Ⅲ (P <0.05). Conclusion The key to improve the curative effect of rectal cancer recurrence patients is close follow-up, early diagnosis, surgeries or surgery-based comprehensive treatment.