论文部分内容阅读
绝大部分肝细胞性肝癌（简称肝癌）病人合并肝硬化。常规肝功能检查对估计肝硬化病人肝切除时围手术期肝脏贮备功能存在明显不足。我们通过动物实验和临床观察，研究吲哚氰绿15分钟潴留率（ICGR15）、精氨酸清除率（Arg－CR）、利多卡因代谢（LID）、肝实质切除率（PHRR）和动脉血酮体比值（KBR）在反映肝功能状态上的实际价值、并根据临床结果进行了综合评定。结果表明上述指标有助于及时地准确了解病人的肝脏功能状态、并提出了术前评分和在估计预后上的意义。
The vast majority of patients with hepatocellular carcinoma (hepatocellular carcinoma) have cirrhosis. Routine liver function tests have obvious deficiencies in estimating liver function during perioperative liver resection. Through animal experiments and clinical observations, we investigated the 15-min retention rate of indocyanine green (ICGR15), arginine clearance (Arg-CR), lidocaine metabolism (LID), hepatic parenchymal resection (PHRR), and arterial blood. The ketone body ratio (KBR) reflects the actual value of liver function status and is comprehensively evaluated based on clinical results. The results show that the above indicators can help to accurately understand the patient’s liver function status in a timely manner, and put forward preoperative scoring and significance in estimating the prognosis.