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用小柴胡汤为主治疗变应性鼻炎６５例，治疗４周显效５２．３％，总有效率９０．８％。扑尔敏治疗的６５例显效４４．６％，总有效率７６．９％。小柴胡汤疗效明显优于扑尔敏（Ｐ＜０．０５），且复发率低（Ｐ＜０．０１）。经小柴胡汤治疗后，患者变应原鼻粘膜激发试验及血液、鼻分泌物嗜酸粒细胞阳性率均显著降低；鼻分泌物ＩｇＡ含量明显升高，而ＩｇＥ含量明显降低。实验研究表明，小柴胡汤对大鼠被动皮肤过敏反应及对豚鼠速发型超敏反应均有显著的抑制作用。
With Xiaochaihu Decoction as the main treatment for allergic rhinitis in 65 cases, 4 weeks markedly effective 52.3%, with a total effective rate of 90.8%. Of the 65 patients treated with chlorpheniramine, 44.6% were effective, and the total effective rate was 76.9%. The curative effect of Xiaochaihu Tang was significantly better than that of chlorpheniramine (P<0.05), and the recurrence rate was low (P<0.01). After Xiaochaihu Decoction treatment, allergic nasal mucosa provocation tests and eosinophils positive rates in blood and nasal secretions were all significantly reduced; IgA levels in nasal secretions increased significantly, while IgE levels decreased significantly. Experimental studies have shown that Xiaochaihu Decoction has a significant inhibitory effect on passive cutaneous anaphylaxis and immediate hypersensitivity in guinea pigs.