Avermectin是一个驱肠虫抗生素,具有广谱高效的特点。除对丝虫有效外,对其它线虫、蜘蛛和昆虫有效,较高剂量时可治疗钩虫病。其中组份B_1氢化后的衍生物伊维菌素(Ivermectin)作用更好,毒性更低。作为动物驱虫剂,0.2mg/kg一次注射就能达到驱虫效果,国外已大量生产,商品名“Ivomec”。经初步临床证明伊维菌素治疗盘尾丝虫具有很好的效果,使用0.03～0.05mg/kg体重的一次剂量后能大大减少“微丝蚴”的数目,28天一疗程后查不出微丝蚴”。在上述剂量下无神经和眼科等不 Avermectin is an anthelmintic antibiotic with a broad spectrum of efficiencies. In addition to effective against filarial worms, it is effective against other nematodes, spiders and insects, treating hookworms at higher doses. Among them, Ivermectin, a hydrogenated derivative of component B_1, has better effect and lower toxicity. As an animal repellent, 0.2mg / kg injection can achieve deworming effect, has been mass-produced abroad, the trade name “Ivomec.” Preliminary clinical evidence of ivermectin treatment of Onchocercia has a good effect, the use of 0.03 ~ 0.05mg / kg body weight after a dose can greatly reduce the number of “microfilariae”, 28 days after the treatment can not find Microfilariae. "No nerve and ophthalmology at the above doses do not