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Two new complexes[Pd(L-phe)_2·2H_2O](1) and[Pd(4,4’-dcbpy)(en)·H_2O](2)(L-phe = L-phenylalanine,4,4-dcbpy = 2,2’-bipyridyl-4,4’-dicarboxylate,en = ethylenediamine)were synthesized and characterized.L-phenylalanine was in situ formed via the hydrolysis of N-(tert-butoxycarbonyl)-L-phenylalanine,and ethylenediamine came from the in situ reaction of piperazine(pip) under hydrothermal conditions.The single-crystal X-ray structure analyses reveal that the Pd(Ⅱ) ion constructs a square planer coordination geometry in complexes 1 and 2,respectively.Complex 1 extends into a 2D layered structure via H-bond interactions and complex 2connects into a 3D network through hydrogen bonds and n-n stacking interactions.The interactions of 1 and 2 with fish sperm DNA(FS-DNA) were examined via UV-Vis absorption spectra and fluorescence spectroscopy.The cleavage reaction for plasmid DNA has been assayed by agarose gel electrophoresis.The results indicate that two complexes interact with DNA and the insertion is the main binding mode.
Two new complexes [Pd (L-phe) _2 · 2H_2O] (1) and [Pd (4,4’-dcbpy) (en) · H_2O] (2) (L-phe = L-phenylalanine, dcbpy = 2,2’-bipyridyl-4,4’-dicarboxylate, en = ethylenediamine) were synthesized and characterized. L-phenylalanine was in situ formed via the hydrolysis of N- (tert-butoxycarbonyl) came from the in situ reaction of piperazine (pip) under hydrothermal conditions. The single-crystal X-ray structure analyzes reveal that the Pd (II) ion constructs a square planer coordination geometry in complexes 1 and 2, respectively. Complex 1 extends into a 2D layered structure via H-bond interactions and complex 2connects into a 3D network through hydrogen bonds and nn stacking interactions. interactions of 1 and 2 with fish sperm DNA (FS-DNA) via via UV-Vis absorption spectra and fluorescence spectroscopy The cleavage reaction for plasmid DNA has been assayed by agarose gel electrophoresis. These results indicate that two complexes interact with DNA and the ins ertion is the main binding mode.