目的　探讨卵巢黏液性囊性肿瘤伴实附壁结节的病理形态、鉴别诊断、良恶性质及其与预后的关系。方法　报道 2例卵巢黏液性囊性肿瘤伴实性附壁结节 ,进行光镜观察和免疫组化染色 ,并复习相关文献。结果　例 1卵巢粘液性囊腺瘤癌变伴多个伴附壁肉瘤样结节形成 ,结节由破骨样巨细胞及单个核细胞构成 ,免疫表型Vimentin(VM)阳性 ;例 2卵巢粘液性囊腺瘤伴附壁平滑肌瘤结节 ,结节内大量梭形细胞 ,呈束状排列 ,免疫表型VM、MSA、Desmin阳性。结论　免疫组化有助于卵巢黏液性囊性肿瘤伴实性附壁结节的诊断及鉴别诊断 Objective To investigate the pathological features, differential diagnosis, benign and malignant features of ovarian mucinous cystic neoplasm complicated with adherent nodules and its relationship with prognosis. Methods Two cases of ovarian mucinous cystic tumor with solid appendage nodules were observed and observed by light microscopy and immunohistochemistry. The related literatures were reviewed. Results Example 1 Ovarian mucinous cystadenocarcinoma is associated with the formation of multiple adjunct sarcomatoid nodules consisting of osteoclastic giant cells and mononuclear cells with positive immunophenotype Vimentin (VM). Case 2 Ovarian mucinous Cystadenoma with attached leiomyoma nodules, a large number of nodules spindle cells arranged in a bundle, immunophenotype VM, MSA, Desmin positive. Conclusions Immunohistochemistry is helpful to the diagnosis and differential diagnosis of ovarian mucinous cystic tumor with solid appearing nodules