1996年2月17—27日,两个挪威人家庭(9人,年龄7—82岁)在尚比亚河地区度假,其中5人从1991—1993年曾在该地区居住过两年。出发前一星期已开始使用氯喹,自出发之日起用氯胍作为预防,回到挪威后,直至入院仍继续服用这两种药。此外,还细心使用驱虫剂和蚊帐。他们度假前,该地区曾下过大雨。他们的旅程包括Hwange国家公园、维多利亚瀑布及尚比亚河。在尚比亚河 Between 17 and 27 February 1996, two Norwegian families (9 persons, ages 7-82) were on vacation in the Zambia region, five of whom had lived in the area for two years from 1991 to 1993. Chloroquine has started to be used one week prior to departure, with proguanil being used as a prophylaxis since the date of departure and returned to Norway until the admission of both drugs. In addition, repellent and mosquito nets are used with care. The area had heavy rain before their holiday. Their journey includes Hwange National Park, Victoria Falls and the Zambian River. In the Zambian River