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本文对４３８例中孕水囊引产病人应用大剂量催产素引产进行了临床观察。结果：４３８例中４２１例１次引产成功，成功率为９６．１２％；平均催产素用量为１８９．２７±１０３．２７￣μ／人，从放置水囊至胎儿排出的全部时间平均为２９．２９±１９．０７ｈ。４３８例病人未出现羊水栓塞、子宫破裂、胎盘早剥及宫颈损伤等严重并发症。提示大剂量催产素用于中孕水囊引产是安全可行的，具有成功率高、排胎时间短、无明显并发症等优点。主要的监测和护理要点是：严格遵守催产素静脉滴注方法；专人看护、严密监测；合理掌握催产素的应用时间及剂量；做好心理护理工作；预防感染，防止产后出血。
In this paper, 438 cases of pregnant women induced abortion in patients with high-dose oxytocin induction of clinical observation. Results: Among the 438 cases, 421 cases achieved successful primary induction of labor with a success rate of 96.12%. The mean oxytocin consumption was 189.27 ± 103.27μμ / person. The mean time from the placement of the water sac to the fetus was 29 .29 ± 19.07h. 438 patients did not appear amniotic fluid embolism, uterine rupture, placental abruption and cervical injury and other serious complications. Prompt high-dose oxytocin for pregnant women in the induction of labor is safe and feasible, with a high success rate, row of short time, no obvious complications and so on. The main monitoring and nursing points are: strict adherence to intravenous infusion of oxytocin; special care, close monitoring; reasonable control of oxytocin application time and dosage; good psychological care; prevent infection and prevent postpartum hemorrhage.