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目的 探讨外科手术治疗胚胎发育不良性神经上皮肿瘤(DNT)继发癫痫的临床疗效及影响预后的相关因素.方法 回顾性分析北京丰台医院癫痫中心2009年11月—2017年11月收治的37例病理证实为DNT的癫痫患者的临床资料.根据Engel分级评估患者的预后;并分析患者的性别、发病年龄、病程、癫痫发作类型、病变部位、影像学特点、切除方式等因素与预后的关系.结果 本组患者术后平均随访(55.4 ± 28.0)个月,其中33例患者(89.2%)术后癫痫发作完全消失(Engel Ⅰ级).分析结果显示,病程越短、病灶切除完全的患者预后越好(均P＜0.05).结论 DNT所致癫痫的手术治疗效果较好,早期、完全切除病变是影响手术预后的重要因素.“,”To explore the clinical prognosis of surgical treatment of epilepsy secondary to dysembryoplastic neuroepithelial tumor ( DNT ) and the related factors affecting the prognosis of epilepsy.Methods The clinical data of 37 epilepsy patients with histologically proved by DNT who were admitted to Epilepsy Center , Beijing Fengtai Hospital from November 2009 to November 2017 were analyzed retrospectively.The relationship between prognosis and gender , age of onset, course of disease , type of epilepsy, location of lesion, imaging features, resection methods and other factors was analyzed.The patients were divided into favorable group ( EngelⅠ) and unfavorable group ( EngelⅡ-Ⅳ) according to postoperative seizure outcome.Statistical methods were analyzed by chi-square test and independent sample t-test.Results 37 patients were followed up for an average of(55.4+28.0) months, and 33 patients(89.2%) had complete disappearance of epileptic seizures(Engel Ⅰ).The analysis showed that short epilepsy duration and completeness of resection would have a favorable seizure outcome (P＜0.05).Conclusions Surgical treatment of epilepsy caused by DNT is effective.Early surgery and completeness of resection are significantly associated with post-operative seizure outcome in epilepsy patients with DNT.