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作者报道1986年元月～1987年5月,用BCG灌注治疗8例上尿路原位癌10次,病人平均年龄74岁(66～86岁)。所有病人均有很长的尿路上皮癌史。治疗方法为在B超引导下用局麻将9F导管作经皮肾造瘘术, 经造瘘管灌注BCG。将360mg BCG溶于生理盐水150ml中,用10～15ml BCG溶液充盈肾盂输尿管系统后,按分钟1ml(15～20滴/分)连续灌注维持,2小时后停止灌注,关闭肾造瘘管。预防性应用氨苄青霉素,住院观察1夜。一周后重复治疗,共6次,拔除肾造瘘管。如6周后尿细胞学检查仍阳性,则再作一疗程。
The authors reported that from January 1986 to May 1987, 8 patients with upper urinary tract carcinoma in situ were treated with BCG infusion 10 times, with a mean age of 74 years (66-86 years). All patients have a long history of urothelial cancer. Treatment is under the guidance of B ultrasound with local anesthesia 9F catheter percutaneous nephrostomy, the fistula perfusion BCG. 360 mg of BCG was dissolved in 150 ml of physiological saline. After the ureteropelvic system was filled with 10-15 ml of BCG solution, continuous infusion of 1 ml (15-20 drops / minute) was continued for 1 minute. Perfusion was stopped after 2 hours and the renal fistula was closed. Prophylactic ampicillin, hospital stay 1 night. Repeat treatment after a week, a total of 6 times, removal of renal fistula. If 6 weeks after urine cytology is still positive, then make a course of treatment.