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目的:为有效改善阑尾脓肿小儿患者临床病症,提高患者生活质量,临床探讨红藤解毒汤联合西药对小儿阑尾脓肿的治疗效果。方法:选取2013年1月—2015年7月于本院住院诊治的80例小儿阑尾脓肿患者,随机分为观察组40例与对照组40例,对照组患儿予以头孢美唑联合替硝唑抗感染为主的西药治疗,观察组患儿在对照组的用药基础上联合运用中药制剂红藤解毒汤治疗,观察与比较两组患儿临床症状、体征改善情况、所需住院时间以及白细胞计数、C-反应蛋白等血清学指标恢复情况,分析治疗效果,统计用药期间不良反应发生情况以及疾病复发情况。结果:观察组患儿的临床症状、体征消退时间及所需住院时间较对照组患儿显著缩短,其差异具有统计学意义,P<0.05;在反映患儿病情程度的炎性因子指标白细胞计数及C-反应蛋白水平上,观察组亦较对照组恢复的程度更好,其差异亦具有统计学意义,P<0.05;两组不良反应发生率相比,对照组为17.5%,观察组为12.5%,两组不良反应发生情况差别无意义(x2=0.980,P>0.05);半年后疾病复发率相比,对照组为为12.5%,观察组为2.5%,观察组较对照组疾病复发少(x2=7.207,P<0.05);同时两组临床有效率比较,观察组总有效率为95.0%,对照组为82.5%,对照组较观察组疗效差(x2=7.825,P<0.05)。结论:针对小儿阑尾脓肿,采取以红藤解毒汤联合西药为主的治疗方案可明显改善患者症状、体征及抑制炎性反应,是有效的、安全的治疗方法,值得临床上进一步应用推广。
Objective: In order to effectively improve the clinical symptoms of children with appendiceal abscess and improve the quality of life of patients, the clinical treatment of pediatric appendiceal abscess with the combination of Hongtu Jiedu Decoction and Western medicine. Methods: Eighty children with appendiceal abscess admitted to our hospital from January 2013 to July 2015 were randomly divided into observation group (40 cases) and control group (40 cases). The control group was given cefmetazole combined with tinidazole Anti-infection-based Western medicine treatment group, children in the observation group in the control group based on the use of traditional Chinese medicine preparation Hongtieddudu Tang treatment, observation and comparison of two groups of children with clinical symptoms and signs of improvement, the required hospital stay and white blood cell count , C-reactive protein and other serological indicators of recovery, analysis of the treatment effect, statistical treatment of adverse reactions and disease recurrence. Results: The clinical symptoms, signs of subsided time and the required hospital stay in observation group were significantly shorter than those in control group, the difference was statistically significant (P <0.05). In the index of inflammatory factors reflecting the severity of the illness, the white blood cell count And C-reactive protein levels, the observation group also recovered better than the control group, the difference was statistically significant, P <0.05; two groups of adverse reactions compared to 17.5% in the control group, the observation group was 12.5% respectively. There was no significant difference between the two groups in incidence of adverse reactions (x2 = 0.980, P> 0.05). After six months, the relapse rate of the disease was 12.5% in the control group and 2.5% in the observation group. (X2 = 7.207, P <0.05). At the same time, the total effective rate was 95.0% in the observation group and 82.5% in the control group, while the control group was less effective than the observation group (x2 = 7.825, P < . Conclusion: The treatment of appendiceal abscess in children with combination of Chinese herbs and red vine detoxification soup can significantly improve the symptoms and signs of patients and inhibit the inflammatory response, which is an effective and safe treatment and is worth further promotion in clinical application.