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提高对非铜绿假单胞菌属严重感染的认识。方法对经血细菌纯培养阳性证实的非铜绿假单胞菌属败血症61例进行分析。结果①男43例,女18例,年龄4天~54岁。②38例(6229%)为院内感染,继发于严重基础病;23例(3771%)为院外原发感染,其中15例(6521%)合并肺炎。③60例(9836%)有发热,15例(25%)有中毒性休克。④血WBC在(20~281)×109·L-1之间,>100×109·L-1者50例(8196%),中性>075者40例(6557%)。⑤嗜麦芽假单胞菌41例,类产碱假单胞菌10例,恶臭假单胞菌6例,洋葱或施氏假单胞菌各2例。⑥对庆大霉素、哌拉西林、头孢他啶耐药率高达3684%~6666%。⑦37例(6065%)治愈出院,8例自动出院,16例(2622%)死亡,9例死于中毒性休克,7例死于原发病。结论非铜绿假单胞属败血症是近几年突出的严重院内感染,细菌多重耐药,病原治疗是一个难题,应引起人们高度重视。
Improve awareness of non-Pseudomonas aeruginosa infection. Methods Sixty-one cases of Pseudomonas aeruginosa septicemia confirmed by blood culture pure culture were analyzed. Results ① 43 males and 18 females, aged 4 days to 54 years old. ②38 cases (6229%) were nosocomial infection, secondary to severe underlying disease; 23 cases (3771%) were primary hospital infection, of which 15 cases (6521%) had pneumonia. ③60 cases (9836%) had fever, 15 cases (25%) had toxic shock. (4) Blood WBC between (2 0 ~ 28 1) × 109 · L-1, 50 cases (8196%)> 10 0 × 109 · L-1, Cases (65 57%). ⑤ 41 cases of Pseudomonas maltophilia, 10 cases of Pseudomonas pseudoalcaligenes, 6 cases of Pseudomonas putida, 2 cases of onion or Pseudomonas stutzeri each. ⑥ on gentamicin, piperacillin, ceftazidime resistance rates as high as 36 84% ~ 66 66%. ⑦ 37 cases (60.65%) were cured and discharged, 8 cases were discharged automatically, 16 cases (26.2%) died, 9 died of toxic shock and 7 died of primary disease. Conclusion Non-Pseudomonas aeruginosa sepsis is a serious and serious nosocomial infection in recent years. Bacterial multi-drug resistance and pathogen treatment are a difficult problem that should be paid great attention to.