生物粘附释药系统作为一种新颖的药物释放系统 ,利用生物粘附聚合物与腔道粘膜间的生物粘附力 ,延长制剂在腔道内的滞留时间 ,控制制剂中药物的释放速度和释放量 ,使制剂产生最佳治疗效果。本文结合国内外有关文献将对该系统在腔道中的应用进行一定的介绍 ,内容主要包括作用机理、粘附材料、粘附释药系统粘附力与溶出度、常用剂型介绍及实际临床应用等。着重突出了该释药系统的临床药用价值 As a novel drug delivery system, bioadhesive drug release system utilizes bioadhesion between bioadhesive polymer and mucous membrane of the cavity to prolong the residence time of the drug in the cavity, and to control the release rate and release of the drug in the preparation The amount of preparation to produce the best therapeutic effect. In this paper, we will introduce the application of the system in the cavity with relevant documents both at home and abroad, including the mechanism of action, adhesion materials and the dissolution rate of the adhesive drug delivery system, introduction of common dosage forms and practical clinical application . The clinical medicinal value of the drug delivery system is highlighted