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人体组织及血液中有机毒(药)物的检验因检材中脂肪、蛋白质杂质的干扰,需进行净化处理。本文实验比较了硅藻土柱、中性氧化铝柱、GDX_103固相萃取柱、无水乙醇、醋酸锌等5种方法的提取净化效果,以供同行在选用时参考。1材料与方法1.1主要仪器与试剂气相色谱/质谱联用仪(安捷伦5973N);毛细管色谱柱:DB-5MS(30m×0.25mm×0.25μm);硅藻土柱、中性氧化铝柱、GDX_103固相萃取柱(以上各柱均购自公安部二所);甲胺磷、丙咪嗪、甲氰菊酯、巴比妥、烯丙异丙巴比妥、乙基对硫磷、可待因、SKF525A、
Human tissue and blood organic toxic (drug) test due to the detection of fat, protein impurities, the need for purification. In this paper, we compared the extraction and purification effects of five methods of diatomite column, neutral alumina column, GDX_103 solid phase extraction column, absolute ethanol, zinc acetate and so on for the reference of peers when choosing. 1 Materials and methods 1.1 Main instruments and reagents GC / MS (Agilent 5973N); capillary column: DB-5MS (30m × 0.25mm × 0.25μm); diatomaceous earth column, neutral alumina column, GDX_103 Solid phase extraction column (the above columns were purchased from the Ministry of Public Security two); methamidophos, imipramine, fenpropathrin, barbital, allyl isobarbital, ethyl parathion, Because, SKF525A,