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目的了解序贯或同时使用米非司酮与依沙吖啶对初产妇中孕引产的效果有无区别,探讨初产妇中孕引产的最佳方法。方法选取2010年1月至2011年6月在本院引产的初产妇60例,随机分成两组,30例先口服米非司酮50mg,Q12h3次,24h后待肝肾功结果回报时行雷引术(观察组),30例行雷引术同时口服米非司酮50mg,Q12h3次(对照组),比较两组的宫缩发动时间、总产程时间、疼痛程度、产后出血量及胎盘胎膜残留率有无区别。结果观察组与对照组的宫缩发动时间及胎盘胎膜残留率差异有统计学意义(P<0.05),而两组的总产程时间、疼痛程度及产后出血量差异无统计学意义(P>0.05)。结论米非司酮及依沙吖啶序贯用于初产妇引产的方法可缩短住院时间,减轻患者经济负担,加快医院病床周转率。
Objective To understand whether sequential or concurrent use of mifepristone and ethacridine has the best effect on the induction of labor in primiparous pregnant women, and to explore the best method for primipara in pregnant women. Methods A total of 60 primiparae were induced in our hospital from January 2010 to June 2011. They were randomly divided into two groups. 30 cases were given oral mifepristone 50mg qd for 3 times. (Observation group) and 30 cases of mifepristone with oral administration of 50 mg of mifepristone and Q12h3 times (control group). The time of contractions, the duration of labor, the duration of pain, the amount of postpartum hemorrhage and the number of placenta Whether the residual rate of membrane difference. Results There was significant difference between the observation group and the control group in the time of uterine contractions and the residual rate of placental membranes (P <0.05). There was no significant difference in the duration of total labor, the degree of pain and the amount of postpartum hemorrhage between two groups (P> 0.05). Conclusion The sequential use of mifepristone and ethacridine for labor induction of primipara leads to shorter hospital stay, less financial burden and faster hospital bed turnover rate.