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目的探讨运动训练对老年冠心病患者左室舒张功能的影响。方法 64例老年冠心病患者随机分为运动训练组(n=32)和常规治疗组(n=32),均接受12 w相同的冠心病药物治疗,运动训练组同时给予运动训练。另选择30例健康老年人为正常对照组。超声心动图评估左室舒张功能和收缩功能,6分钟步行距离试验(6MWD)评估运动耐量。结果治疗前,与正常对照组相比,两组患者左室舒张参数A明显增高(P<0.05),E、E/A比值明显降低(P<0.05);两组患者的6MWD均显著短于正常对照组(P<0.05);两组患者左室收缩功能均在正常范围。治疗后,常规治疗组和运动训练组患者E、A、E/A参数均有所改善,运动训练组参数E、A、E/A比值优于常规治疗组(P<0.01);两组患者的步行距离均有增加,运动训练组较常规治疗组增加更显著(P<0.01);两组患者左室收缩功能无明显改变(P>0.05)。结论运动训练能改善老年冠心病患者的左室舒张功能和运动耐量。
Objective To investigate the effect of exercise training on left ventricular diastolic function in elderly patients with coronary heart disease. Methods Sixty-four elderly patients with coronary heart disease were randomly divided into exercise training group (n = 32) and conventional treatment group (n = 32). All patients received coronary heart disease for 12 weeks. Exercise training group was given exercise training at the same time. Another 30 healthy elderly were selected as normal control group. Echocardiographic assessment of left ventricular diastolic function and systolic function, 6-minute walking distance test (6MWD) to assess exercise tolerance. Results Before treatment, left ventricular diastolic parameter A (P <0.05) and E, E / A ratio (P <0.05) were significantly decreased in both groups compared with those in normal control group Normal control group (P <0.05); left ventricular systolic function in both groups were in the normal range. After treatment, the parameters of E, A, E / A in both the conventional treatment group and the exercise training group were improved, and the parameters E, A and E / A in exercise training group were better than those in the conventional treatment group (P <0.01) (P <0.01). There was no significant change in left ventricular systolic function between the two groups (P> 0.05). Conclusion Exercise training can improve left ventricular diastolic function and exercise tolerance in elderly patients with coronary heart disease.