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目的:探讨Ⅱ型糖尿病(T2DM)并发代谢综合征(MS)与心脏自主神经病变(CAN)之间的相关性。方法:根据是否并发MS将438名T2DM患者分为MS组及非MS组,比较两组间CAN发病率的差异,并进行相关及回归分析。结果:MS组的CAN发病率显著高于非MS组,且MS组分与心脏自主神经功能检查得分之间呈正相关;多因素Logistic回归分析显示,糖尿病病程、收缩压、三酰甘油及糖化血红蛋白为CAN发生的高危因素。结论:MS与T2DM的CAN之间密切相关。
Objective: To investigate the relationship between type 2 diabetes mellitus (T2DM) complicated with metabolic syndrome (MS) and cardiac autonomic neuropathy (CAN). Methods: 438 T2DM patients were divided into MS group and non-MS group according to whether they were complicated with MS. The difference of CAN incidence between the two groups was compared and the correlation and regression analysis were performed. Results: The incidence of CAN in MS group was significantly higher than that in non-MS group, and there was a positive correlation between MS score and cardiac autonomic nervous function score. Multivariate Logistic regression analysis showed that duration of diabetes, systolic blood pressure, triglyceride and glycosylated hemoglobin High-risk factors for CAN. Conclusion: There is a close relationship between MS and CAN in T2DM.