高原低压低氧环境可在一定程度上引起人体生理和心理上的应激反应。以往的研究发现,学习记忆能力在高原低压低氧环境下会受到抑制,其原因可能与中枢神经系统发生的一系列病理生理改变有关,如钙稳态紊乱、线粒体损伤、氧化应激以及细胞骨架结构改变等,较严重的是缺氧引起的海马神经元细胞凋亡。但也有不一致的研究报道,急性低压低氧对成年大鼠的学习记忆功能没有影响,甚至有促进作用。本文依托人工实验舱平台,模拟高海拔,观察成年大鼠认知行为学相关评价指 Low altitude hypoxia environment can cause physiological and psychological stress response to a certain extent. Previous studies have found that learning and memory abilities are inhibited in the low altitude hypoxia environment, which may be related to a series of pathophysiological changes in the central nervous system, such as calcium homeostasis, mitochondrial damage, oxidative stress and cytoskeleton Structural changes, more serious hypoxia-induced apoptosis of hippocampal neurons. However, there are also inconsistent studies have reported that acute hypobaric hypoxia has no effect on the learning and memory function of adult rats, and even promote. In this paper, artificial laboratory module platform to simulate high altitude, adult cognitive cognitive behavior related evaluation index