dNTP库平衡对遗传稳定有重要意义,库失衡将引发一系列遗传效应,特别是对细胞自发性和诱导性突变率有重要影响。dNTP库失衡诱发的突变以替换为主的单碱基对事件。 The dNTP pool balance is of great significance for genetic stability. Librariasis imbalance will trigger a series of genetic effects, especially on the spontaneous and inducible mutation rates of cells. Unbalanced dNTP-induced mutations were replaced by predominantly single-base pair events.