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该文归纳了脑梗死形成的6条危险因素,总结了脑梗死现阶段溶栓、改善微循环、抗凝、降低颅内压、神经细胞保护、基因、中医、血液平衡及骨髓间质干细胞等治疗进展情况。脑梗死是基因治疗的潜在目标。碱性成纤维细胞生长因子(bFGF)对缺血性脑损伤有神经保护作用;凋亡抑制基因(bcl-2)转基因技术可使脑梗死体积缩小。中医治疗脑梗死效果明显。川芎嗪能改善急性脑循环障碍,使异常的血流状态转为正常的血流状态;灯盏细辛注射液具有舒张脑血管、增加脑血流、改善微循环、清除自由基等作用。骨髓间质干细胞治疗脑梗死研究已取得进展,未来骨髓间质干细胞在治疗脑梗死中会发挥重要作用。
This article summarizes the six risk factors for the formation of cerebral infarction, summarizes the current stage of cerebral infarction thrombolysis, improve microcirculation, anticoagulation, reduce intracranial pressure, nerve cell protection, genes, Chinese medicine, blood balance and bone marrow mesenchymal stem cells Treatment progress. Cerebral infarction is a potential target for gene therapy. Basic fibroblast growth factor (bFGF) has neuroprotective effects on ischemic brain injury. The apoptosis-inhibiting gene (bcl-2) transgenic technique can reduce the volume of cerebral infarction. Chinese medicine treatment of cerebral infarction obvious effect. Ligustrazine can improve the acute cerebral circulation disorder and make the abnormal blood flow state turn into the normal blood flow state. The Erigeron breviscapus injection has the functions of relaxing cerebrovascular, increasing cerebral blood flow, improving microcirculation and eliminating free radical. Bone marrow mesenchymal stem cells for cerebral infarction has made progress in the future, bone marrow mesenchymal stem cells in the treatment of cerebral infarction will play an important role.