将69例病人随机分成两组,分别给予二甲双胍联合胰岛素强化治疗和单独胰岛素强化治疗,3月后分别测两组患者的体重、发生低血糖的频率、及胰岛素用量。结果:二甲双胍联合组患者体重指数、发生低血糖的频率及胰岛素用量均较单独胰岛素强化治疗组为低。 Sixty-nine patients were randomly divided into two groups. Patients were given metformin combined with intensive insulin therapy and insulin alone. After 3 months, the body weight, frequency of hypoglycemia and insulin dosage were measured in both groups. Results: The body mass index, frequency of hypoglycemia and insulin dosage were lower in metformin combined group than those in insulin-alone intensive treatment group.