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目的了解怀化市健康人群麻疹抗体水平和人群免疫状况,为有效地实施麻疹预防措施和控制策略提供科学依据。方法 2010年对7个年龄组共347名健康人群采集静脉血,用酶联免疫吸附试验法进行麻疹特异性LgG抗体水平检测。结果麻疹抗体阳性率为86.74%。不同区(县)麻疹抗体阳性率之间差异无统计学意义(χ2=3.47,P>0.05);不同年龄组麻疹抗体阳性率差异有统计学意义(χ2=41.64,P≤0.05);男性与女性麻疹抗体阳性率之间差异无统计学意义(χ2=0.37,P>0.05);城市与农村抗体阳性率之间差异无统计学意义(χ2=0.49,P>0.05)。结论该市健康人群麻疹抗体水平低于95%,为实现消除麻疹目标,应在大年龄组儿童、育龄妇女及成人中进行麻疹疫苗接种,提高并维持全人群较高的麻疹抗体水平。
Objective To understand the level of measles antibody and immune status in healthy population in Huaihua City, and provide a scientific basis for the effective implementation of measles prevention and control strategies. Methods In 2010, blood samples were collected from 347 healthy people in 7 age groups and measles-specific LgG antibody levels by enzyme-linked immunosorbent assay (ELISA). Results The positive rate of measles antibody was 86.74%. The positive rates of measles antibody in different districts and counties were not statistically different (χ2 = 3.47, P> 0.05). The positive rates of measles antibody in different age groups were statistically different (χ2 = 41.64, P≤0.05) There was no significant difference between the positive rate of measles antibody in females (χ2 = 0.37, P> 0.05). There was no significant difference between the antibody positive rates in urban and rural areas (χ2 = 0.49, P> 0.05). Conclusion The level of measles antibody in healthy population is less than 95%. To achieve the goal of measles elimination, measles vaccination should be carried out in children of large age group, women of childbearing age and adults to raise and maintain high measles antibody level in the entire population.