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干扰素是在一定的诱生剂的作用下,由细胞分泌的一类蛋白质,它具有广谱抗病毒、抗肿瘤以及免疫调节作用.目前已有一些国家在临床上试用干扰素治疗多种病毒性疾病和恶性肿瘤,取得了较为满意的结果.目前国内一些单位已能少量生产干扰素,并已运用于临床.但由于不能大批生产,故还不能广泛用于临床治疗病人. 一、干扰素的本质 1957年英国病毒学家艾萨克斯(Isaacs)等发现了干扰素.近年来对干扰素的研究有突飞猛进的发展.干扰素是由干扰素诱生剂诱导有关细胞编码的蛋白质,即由其基因脱氧核糖核酸(DNA)转录形成信使核糖核酸(mkNA),再翻译成干扰素蛋白多肽.分泌到细胞外的干扰素大多以糖蛋白的形式出现,
Interferon is a kind of protein secreted by cells under the action of certain inducer, which has a broad spectrum of antiviral, anti-tumor and immunomodulatory effects.At present, some countries have tried interferon in clinic to treat various viruses Sexually transmitted diseases and malignant tumors have achieved more satisfactory results.At present, some domestic units have been able to produce small amounts of interferon and have been used in clinical.But because of mass production, it can not be widely used in clinical treatment of patients .A interferon In 1957, Britain’s virologist Isaacs found interferon.In recent years, research on interferon has progressed by leaps and bounds.Interferon is a protein induced by interferon inducing cell-related protein, that is, Gene DNA (DNA) transcription to form messenger ribonucleic acid (mkNA), and then translated into interferon protein polypeptide. The secretion of extracellular interferon mostly glycoprotein form,