血清透明质酸测定对肝病诊断的意义中国人民解放军白求恩国际和平医院（０５００８２）王锡育，赵占武，王法印，刘广荣，孙晓燕，胡金弟透明质酸（ＨＡ）是近几年才被注意的一项新指标，据国外报道［１－８］，血清ＨＡ在肝病、肿瘤和结缔组织等疾病时增加。国内对此研究甚少，为了进一步了解ＨＡ在肝脏疾病中意义，我们对ｌｌ８例肝病患者和６６名健康成人（对照组）进行了检测，现报道如下：资料和方法一、检测对象本组ｌｌ８例均为住院患者。诊断按１９９０年上海第六次全国病毒性肝炎会议修订的临床诊断标准。其中急性肝炎（急肝）４３例（黄疸型１３例，无黄疸型３０例），慢迁肝１７例，慢活肝３０例，肝炎后肝硬化２８例（代偿期１６例，失代偿期１２例）。男９０例，女２８例。年龄９～６５岁，平均３１．８岁。对照组系６６名健康成人。男５１名，女１５名。年龄２０～４８岁，平均３０．６岁。检测的患者均无心、肾、肺及结缔组织等合并症。二、方法检测对象晨起空腹采血，同时做肝功能等检查。ＨＡ分析药盒由上海第二军医大学长征医院及海军医学研究所提供。统计学处理用Ｔ及Ｘ２检验和相关系数显著性检验。结果一、对照组及各型肝病组血清ＨＡ值见表１。从表ｌ可见，除慢迁肝组外，其余三 Serum hyaluronic acid determination of the significance of the diagnosis of liver disease People’s Liberation Army Bethune International Peace Hospital (050082) Wang Xiyu, Zhao Zhanwu, Wang Feinu, Liu Guangrong, Sun Xiaoyan, Hu Jindi Hyaluronic acid (HA) is only noticed in recent years, a new indicator , According to foreign reports [1-8], serum HA in liver disease, cancer and connective tissue and other diseases increased. Domestic little research on this, in order to further understand the significance of HA in liver disease, we ll8 patients with liver disease and 66 healthy adults (control group) were tested, are reported as follows: Materials and methods First, the detection of this group ll8 Cases are hospitalized patients. The diagnosis was based on the revised clinical diagnostic criteria of the Sixth National Viral Hepatitis Meeting in Shanghai in 1990. There were 43 cases of acute hepatitis (acute liver disease), 13 cases of jaundice and 30 cases of jaundice, 17 cases of slow-moving liver, 30 cases of slow-living liver and 28 cases of post-hepatitis cirrhosis (16 cases of decompensation, decompensation Period of 12 cases). 90 males and 28 females. Aged 9 to 65 years old, average 31.8 years old. The control group of 66 healthy adults. 51 males and 15 females. Age 20 to 48 years old, average 30.6 years old. Patients were detected without heart, kidney, lung and connective tissue complications. Second, the method of test subjects morning fasting blood, liver function tests at the same time. HA analysis kit by the Shanghai Second Military Medical University Changzheng Hospital and Naval Medical Research Institute. Statistical analysis using T and X2 test and correlation coefficient significance test. Results One, the control group and various types of liver disease serum HA value in Table 1. Can be seen from Table l, in addition to slow-moving liver group, the remaining three