近几年云南某些县在抗疟第一线的不少医务人员反映氯喹效果不够满意,似乎恶性疟原虫对氯喹有抗药性。关于恶性疟原虫对氯喹抗药性问题,在国内尚未见有系统的报告。我们同六三医院、孟定公社卫生所医护人员协作,在云南的耿马县孟定地区,于1973年7～9月进行了恶性疟原虫对氯喹的临床敏感性观察,其结果报告如下。 In recent years, some counties in Yunnan Province in the first line of malaria many of the medical staff to reflect the chloroquine effect is not satisfactory, it seems that Plasmodium falciparum chloroquine resistance. There is no systematic report on the resistance of Plasmodium falciparum to chloroquine in China. In collaboration with medical staff of the Sixth and Third Hospital and Mengding Community Health Center, we observed the clinical susceptibility of Plasmodium falciparum to chloroquine from July to September 1973 in Mengding, Gengma County, Yunnan Province. The results are reported below.