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目的比较Ｂ超、ＣＴ、９９ｍＴｃ甲氧基异丁基异腈（ＭＩＢＩ）对于高功能甲状旁腺病灶定位诊断的价值。方法经临床诊断为原发性甲状旁腺机能亢进（简称原发甲旁亢）的２３例患者均做了Ｂ超检查，２０例做了ＣＴ扫描，２１例进行了９９ｍＴｃＭＩＢＩ核素显像。结果２３例患者共摘除２３枚腺瘤和２枚增生腺体，均经病理诊断证实。Ｂ超、ＣＴ、９９ｍＴｃＭＩＢＩ的灵敏度分别为６０％、６８％和９１％，特异性为９７％、９７％和１００％，准确性为８９％、９１％和９８％。Ｂ超与ＣＴ无明显差异，９９ｍＴｃＭＩＢＩ在灵敏度和准确性方面优于Ｂ超和ＣＴ，但特异性三者近似。结论９９ｍＴｃＭＩＢＩ双时相法对于甲状旁腺腺瘤的定位诊断很有帮助，原发甲旁亢患者首次探查术前进行无创影像定位检查是必要的
Objective To compare the diagnostic value of B-ultrasonography, CT, 99mTc-methoxyisobutylisonitrile (MIBI) in the diagnosis of hyperfunctioned parathyroid lesions. Methods Twenty-three patients with primary hyperparathyroidism (primary hyperparathyroidism) were clinically diagnosed as B-ultrasound, CT scan was performed in 20 cases and 99mTc-MIBI imaging was performed in 21 cases . Results Totally 23 adenomas and 2 proliferative glands were removed in 23 patients, all confirmed by pathological diagnosis. The sensitivity of B-ultrasound, CT, 99mTc-MIBI was 60%, 68% and 91% respectively, and the specificity was 97%, 97% and 100% with accuracy of 89%, 91% and 98% respectively. There was no significant difference between B ultrasound and CT. 99mTcMIBI was superior to B ultrasound and CT in sensitivity and accuracy, but the specificity was similar. Conclusion 99mTcMIBI dual-phase method for the diagnosis of parathyroid adenoma is helpful in the diagnosis of primary hyperparathyroidism for the first time before noninvasive imaging mapping is necessary